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外周神经阻滞时术中镇静对老年患者心率变异性的影响 被引量:1

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摘要 目的 观察靶控输注咪达唑仑和普鲁泊福镇静时老年患者心率变异性(HRV)的变化.方法 选择在外周神经阻滞下行四肢手术的老年患者30例,按随机数字表法分为普鲁泊福组和咪达唑仑组,每组15例.比较两组的平均动脉压(MAP)、心率及HRV指标.结果 普鲁泊福组意识恢复时间[(6.3±1.3)min]明显短于咪达唑仑组[(15.4±3.1)min](P<0.05).随着镇静程度的加深,咪达唑仑组低频成分(LF)、LF标准化值(nuLF)、LF/高频成分(HF)、总功率(TP)和MAP逐渐降低,HF标准化值(nuHF)逐渐升高.普鲁泊福组中HF、LF、nuHF、nuLF和TP随着镇静程度的加深明显降低,尤以HF降低为明显,LF/HF有上升趋势.结论 咪达唑仑主要抑制交感神经活性,而普鲁泊福主要抑制副交感神经活性.
出处 《中国医师进修杂志》 2011年第12期33-34,共2页 Chinese Journal of Postgraduates of Medicine
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