Investigation of pressure loading rates on streaming potentials in bone

When load is applied to bone,it deforms and causes fluid pressure to build up in bone.The pressure gradient between different portions of the bone microcnannels drives fluid flow through them.This kind of bone fluid flow can induces the streaming potentials which are considered to play a role for bone remodeling.Aimed to determine the impact of ribbed rough inner surfaces of the microchannels on the streaming potentials,streaming potentials were measured as bone fluid flowed through the mcrospaces of thin cylinder bone samples under different pressure loading rates.The results show that the streaming potentials decrease with the increase of the pressure loading rates.A digital simulation calculation was performed and the results demonstrated that there were turbulent flows near the inner wall surfaces,which making the streaming potentials smaller in bone microchannels.