药用植物内生真菌生物活性及其活性成分研究

Research Progress of Biological Activity and Active Components of Endophytic Fungus from Medicinal Plants

内生真菌在药用植物内普遍存在,并且具有重要的生物活性,如抗菌、抗氧化及抗肿瘤活性,因此,内生真菌已成为活性代谢产物的一个新的来源。文章主要介绍了内生真菌的生物活性、阐述了其能够产生与宿主植物相同或类似的活性成分的特点以及总结了近年来内生真菌产生的重要活性物质并对其进行了分类。同时,对内生真菌的发展前景进行了初步的探讨,以期为药用植物内生真菌的应用提供理论依据。

Endophytic fungusis is broadly present in medicinal plants and possesses important biological activities including anti-microbes,anti-oxidant and anti-tumor.Therefore,endophytic fungus became a new resource of bioactive metabolites.In this paper,the biological activities of endophytic fungus were introduced,the characteristic of producing identical or akin active components with host plants was described and the important identical secondary metabolites were summarized.The prospect of endophytic fungus was also indicated.This paper could provide the basic theories for endophytic fungus from medicinal plants.