近期微流控芯片疾病诊断技术的研究进展

Recent development of microfluidic diagnostic technologies

微流控芯片具有液流可控、样品消耗量小、反应速度快、易于集成化等特点,在临床诊断和疾病筛查领域具有广阔的发展前景。本文针对近年来微流控芯片技术在疾病诊断方面的最新研究进展,从疾病标志物检测、细胞筛选和药物代谢研究及疾病诊断微流控芯片装置的发展现状等方面概述其在疾病诊断方面的应用和发展。

Microfluidic devices exhibit a great promising development in clinical diagnosis and disease screening due to their advantages of precise controlling of fluid flow,requirement of miniamount sample,rapid reaction speed and convenient integration.In this paper,the improvements of microfluidic diagnostic technologies in recent years are reviewed.The applications and developments of on-chip disease marker detection,microfluidic cell selection and cell drug metabolism,and diagnostic micro-devices are discussed.