我院呼吸科下呼吸道感染患者的细菌种类及耐药性分析

Analysis of Types and Drug Resistance of Bacteria in Patients with Lower Respiratory Tract Infection in Respiratory Department of Our Hospital

目的:分析下呼吸道感染患者痰液标本中细菌群的构成及耐药情况,为临床医师用药提供科学依据。方法:384份送检标本共培养出病原菌245株,对菌种鉴定和药敏试验结果进行分析。结果:真菌52株(占21.2%),革兰阳性球菌34株(占13.9%),革兰阴性杆菌159株(占64.9%)。前8位主要病原菌分别是副流感嗜血杆菌、肺炎克雷伯菌、鲍曼不动杆菌、铜绿假单胞菌、溶血葡萄球菌、大肠埃希菌、肺炎链球菌、金黄色葡萄球菌。结论:下呼吸道感染以革兰阴性杆菌为主,常见病原菌耐药现象比较严重,应注意合理用药。

OBJECTIVE：To analyze the composition and drug resistant of bacteria colonies in sputum specimens of patients with lower respiratory tract infection,and to provide scientific basis for clinicians about medication.METHODS：245 strains of pathogenic bacteria were cultured in 384 specimens.Results of bacteria strain identification and drug sensitivity test were analyzed.RESULTS：There were 52 strains of fungi （21.2%）,34 strains of gram-positive bacterium （13.9%）,159 strains of gram-negative bacterium （64.9%）.Top 8 pathogenic bacteria were Hemophilus parainfluenzae,Klebsiella pneumoniae,Acinetobacter baumannii,Pseudomonas aeruginosa and Staphylococcus haemolyticus,Escherichia coli,Streptococcus pneumoniae,Staphylococcus aureus.CONCLUSION：Gram-negative bacteria are the main pathogens of infection,and drug resistance of common pathogens is quite serious.Great importance should be attached to rational drug use.