踏车运动锻炼对下肢外周动脉疾病者运动功能的影响

Effect of Treadmill Exercise on the Function of Lower Extremities

[目的]探讨踏车运动锻炼对下肢外周动脉疾病（peripheral arterial disease,PAD）患者运动功能的影响.[方法]本院118例下肢PAD患者,随机分为研究组和对照组.两组在接受相同的PAD药物治疗的基础上,研究组接受有监视的踏车运动锻炼6个月,对照组不接受踏车运动锻炼.研究前和研究结束时行6分钟步行实验、记录踏车运动表现和超声测肱动脉血流介导的血管内皮功能.[结果]与对照组比较,研究组6分钟步行距离、踏车运动表现（最长踏车运动时间和下肢发生缺血症状最长距离）和肱动脉血流介导的血管内皮功能明显改善（P＜0.01）.[结论]踏车运动锻炼可提高下肢PAD患者6分钟步行距离,延长最长踏车运动时间和最长踏车距离,改善肱动脉血流介导的血管内皮功能.

[Objective]To explore the effect of treadmill exercise on the function of patients with peripheral arterial disease（PAD） in lower extremities. [Methods] Totally 118 adults in our hospital were randomly divided into study group（ n =59） and control group（ n =59）. Both groups received the same drug treatment of PAD. The study group was additionally given 6-month supervised treadmill exercise, and the control group was not given treadmill exercise. Before and after study, 6-rninute walk experiment was done, and treadmill exercise performance was recorded, and brachial artery flow-mediated vascular endothelial function was measured by ultrasound. [Results]Compared with the control group, 6-rninute walk distance, treadmill exercise performance（maximal treadmill walk time and maximal distance to the onset of ischemic leg symptoms） and brachial artery flow-mediated vascular endothelial function im- proved obviously（ P 〈0.01）. [Conclusion] Treadmill exercise training can increase 6-minute walk distance and the maximal treadmill exercise time of patients with PAD in lower extremities, and improve the brachial artery flow-mediated vascular endothelial function.