内镜下微波联合抗幽门螺杆菌治疗疣状胃炎的临床疗效观察

Clinical Observation on the Efficacy of Endoscopic Microwave Combined with Helicobacter Pyiori Eradication for the Treatment of Gastritis Verrucosa

[目的]观察内镜下微波联合药物抗幽门螺杆菌（Hp）治疗疣状胃炎的临床疗效.[方法]经胃镜诊断而且Hp阳性102例疣状胃炎患者,按检查顺序分为A、B两组,每组51例.A组在胃镜下对所有成熟型疣状病变进行内镜下微波治疗,术后予Hp根除治疗.B组只予Hp根除治疗.比较两组患者疗程结束后4周时Hp根除率和成熟型疣状病变治愈率.[结果]A、B两组在疗程结束后4周Hp根除率分别为92.2%和90.2%,差异无显著性（P〉0.05）,成熟型疣状病变治愈率分别为93.4%和7.1%,有显著差异（P〈0.01）.[结论]内镜下微波联合抗Hp治疗,疗效确切、安全、治疗成本低,是当前治疗疣状胃炎较为理想的一种方法.

[Objective] To observe the clinical efficacy of endoscopic microwave combined with Helicobacter pylori（Hp） eradication for the treatment of gastritis verrueosa. [Methods] Totally 102 cases of gastritis verrucosa with Hp infection diagnosed by gastroscopy were divided into group A（ n = 51） and group B（ n = 51） according to the sequence of examination. All mature verrueous lesions in group A were treated with mierowave therapy under gastroseopy, and then given Hp eradication. Group 13 was only given Hp eradication. The eradication rate of Hp and the curative rate of mature verrucous lesion were compared between two groups 4 weeks at the end of the course. [Results] The eradication rate of Hp in group A and group B was 92.2% and 90. 2%, respectively, and there was no significant difference（ P 〉0.05）. The curative rate of mature verrucous lesion in group A and group B was 93.4 % and 7.1%, and there was significant difference between two groups（ P 〈0.01）. [Conclusion] Endoscopic microwave therapy combined with Hp eradication is effective, safe, and cheap. Therefore it is an ideal method for the treatment of gastritis verrucosa.