丝裂原活化蛋白激酶信号通路与激素非依赖性前列腺癌的关系及治疗进展
被引量:2
摘要
雄激素非依赖性前列腺癌(AI Pca)的发病机制至今不明。近年发现Ras/丝裂原活化蛋白激酶(MAPK)信号通路在前列腺癌病程演变中起重要作用,组成这个信号通路的许多重要蛋白质被认为是AI Pca潜在的药物治疗靶点。作者就Ras/MAPK信号通路在前列腺癌进展中的作用及目前针对该信号通路的抗前列腺癌药物治疗的应用前景做一综述。
出处
《现代泌尿外科杂志》
CAS
2011年第2期184-186,共3页
Journal of Modern Urology
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