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丝裂原活化蛋白激酶信号通路与激素非依赖性前列腺癌的关系及治疗进展 被引量：2

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摘要 雄激素非依赖性前列腺癌(AI Pca)的发病机制至今不明。近年发现Ras/丝裂原活化蛋白激酶(MAPK)信号通路在前列腺癌病程演变中起重要作用,组成这个信号通路的许多重要蛋白质被认为是AI Pca潜在的药物治疗靶点。作者就Ras/MAPK信号通路在前列腺癌进展中的作用及目前针对该信号通路的抗前列腺癌药物治疗的应用前景做一综述。
作者 袁雪锋 刘军 孙宏斌
机构地区 南京市第一医院泌尿外科
出处 《现代泌尿外科杂志》 CAS 2011年第2期184-186,共3页 Journal of Modern Urology
关键词 Ras/MAPK信号通路 前列腺癌 雄激素非依赖性
分类号 R697 [医药卫生—泌尿科学]
  • 相关文献

参考文献18

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二级参考文献24

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共引文献12

同被引文献19

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二级引证文献5

现代泌尿外科杂志
2011年 第2期

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