转录因子CCAAT增强子结合蛋白β(C/EBPβ)的研究进展

Progress of transcription factor CCAAT enhancer binding protein β

CCAAT增强子结合蛋白β(CCAAT enhancer binding protein,C/EBPβ)是CCAAT增强子结合蛋白家族的一员。该家族是碱性亮氨酸拉链大家族的一个亚家族,在细胞分化、能量代谢、生长发育等多个进程中发挥作用。文章就C/EBPβ的结构、表达调控和生物学功能做一综述,并对研究应用进行了展望。

CCAAT enhancer binding protein β（C/EBP β） belongs to CCAAT enhancer binding protein（C/EBP） family,which is a subfamily of basic leucine zipper（bZIP） protein family.C/EBP family plays important roles in many processes such as cell differentiation,metabolism,and development.In this paper,the structure,expression regulation,and function of C/EBP β were reviewed.