甲状腺乳头状癌的灰阶超声造影特征与颈部淋巴结转移的关系

Correlation between gray scale contrast-enhanced ultrasonographic characteristics of papillary thyroid carcinoma and cervical lymph node metastasis

目的:探讨甲状腺乳头状癌(PTC)的灰阶超声造影特征及其与颈部淋巴结转移的关系。方法:用灰阶超声造影评估49例PTC患者的50个结节,并根据颈部淋巴结转移情况将其分为颈部淋巴结未转移组和颈部淋巴结转移组,主要观察癌结节的灌注情况,并分析造影时间-强度曲线(time-intensity curve,TIC),探讨各灰阶超声造影特征与颈部淋巴结转移间的关系。结果:灰阶超声造影显示,与颈部淋巴结转移有关的超声特征主要是灌注动力学和造影TIC的始增时间(T0)、峰值时间(TP)及始增时间差。结论:特定的灰阶超声造影特征可在一定程度上提示PTC患者发生颈部淋巴结转移的可能性,对外科手术的术式选择有一定指导作用。

Objective To investigate the correlation between gray scale contrast-enhanced ultrasonographic characteristics of papillary thyroid carcinoma（PTC） and cervical lymph node metastasis.Methods Gray scale contrast-enhanced ultrasonography was performed in 49 patients with 50 PTC lesions.The patients were categorized into 2 groups,with no lymph node metastases and with lymph node metastases.Gray scale contrast-enhanced ultrasonography was used for examining the perfusion of cancer nodules and the time-intensity curve（TIC） of contrast enhancement was analyzed,and then to study the correlation between the characteristics of gray scale contrast-enhanced ultrasonography and cervical lymph node metastasis.Results The correlation between characteristics of gray scale contrast-enhanced ultrasonography and cervical lymph node metastasis was mainly in the perfusion dynamics and the time begin to enhance,time to peak intensity and time delay for begin of enhancing in TIC.Conclusions Some characteristics of gray scale contrast-enhanced ultrasonography could predict in certain degree the occurrence of cervical lymph node metastasis in papillary thyroid cancer and provide some references for the selection of appropriate surgical mode.