摘要
Aithough the key discovery of sex-deter- mining region Y （SRY） 20 years ago as the essential sex-determining gene emerged from studies of sex-reversed humans, most of our knowledge of how male and female germ cells diverge after sex determination comes from studies of mice. This is demonstrated in a recent publication from Bowles and colleagues in Developmental Cell, which documents the functional importance of fibroblast growth factor 9 （FGFg） signalling in murine fetal germ cells.
Aithough the key discovery of sex-deter- mining region Y （SRY） 20 years ago as the essential sex-determining gene emerged from studies of sex-reversed humans, most of our knowledge of how male and female germ cells diverge after sex determination comes from studies of mice. This is demonstrated in a recent publication from Bowles and colleagues in Developmental Cell, which documents the functional importance of fibroblast growth factor 9 （FGFg） signalling in murine fetal germ cells.
