上海市高知女性跟骨骨密度测定:197个结果分析

Calcaneus bone density of senior intellectual females in Shanghai:Analyzing results from 197 cases

背景:研究表明,女性骨峰值低于男性,而不同地区人群骨矿含量存在差异,因此有必要建立各地区不同人群的峰值骨密度。目的:调查上海市高知女性骨密度随年龄、体质量指数等变化规律。方法:纳入27～62岁高知女性受试者共197例,5岁为一个年龄段,共分为7组。准确记录各组受试者年龄,身高及体质量,并采用超声波骨密度仪测定各组受试者跟骨骨密度。用逐步回归分析各组骨峰值与年龄、体质量和握力的相关性。结果与结论:研究结果显示上海市女性骨量峰值出现在38～39岁年龄段。骨密度值的下降率在31～35岁和41～45岁下降幅度最大。逐步回归分析结果显示,上海高知女性骨峰值与年龄、体质量、握力成正相关,年龄对骨峰值的影响最为明显,峰值骨量越低或出现越早,发生骨质疏松的危险越大。结果表明上海市高知女性群体发生骨质疏松的危险性较大。

BACKGROUND：Studies have demonstrated that the peak bone mass in women is lower than that in men,and value varies wildly in different regions,thus,it is necessary to measure peak bone mass values in each region.OBJECTIVE：To investigate the change laws of calcaneus bone density with age,body mass index（BMI） values and other variations of senior intellectual females in Shanghai.METHODS：Totally 197 females were included and divided into 7 groups with 5-year intervals.The age,height,body weight,and calcaneus bone density of subjects were recorded.The correlation between peak bone mass and age,body weight or grasp force were analyzed by stepwise regression analysis.RESULTS AND CONCLUSION：The results showed that the peak of calcaneus bone density of senior intellectual females in Shanghai appeared at 38-39 years.The decline rate of bone density values biggest dropped in 31-35 years and 41-45 years.Stepwise regression analysis showed the peak bone mass was positive to age,body weight or grasp force,especially age,which obviously affects peak bone mass.Low or early peak bone mass would result in high risk of osteoporosis.It is revealed that compared to normal women,the senior intellectual females are at greater risk of osteoporosis in Shanghai.