N-乙酰转移酶2与皮肤疾病相关研究进展
摘要
N-乙酰基转移酶(N-acetyltransferase,NATs)是大多数哺乳动物体内参与Ⅱ相乙酰化反应的代谢酶。乙酰化反应的多态性导致个体之间不同药物代谢、致癌物质、以及多种外来物质生物代谢之间的不同。NAT2的遗传多态性和组织特异性表达,加上环境因素与NAT2之间的相巨作用,共同影响着人类对某些疾病的易感性。目前国内外一些研究NAT2基因多态性与膀胱癌,
出处
《中国误诊学杂志》
CAS
2011年第6期1274-1275,共2页
Chinese Journal of Misdiagnostics
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共引文献3
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