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多西他赛与顺铂单药及联合治疗晚期非小细胞肺癌疗效观察 被引量:11

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摘要 目的比较多西他赛单药、顺铂单药以及两药联合三种方案治疗晚期非小细胞肺癌(NSCLC)的疗效。方法 104例经病理确诊无手术指征的晚期NSCLC患者。多西他赛组给予艾素75 mg/m2,顺铂组给予顺铂100 mg/m2,联合组给予艾素75 mg/m2加顺铂80 mg/m2。比较三个化疗方案反应率、中位生存期、1 a生存率。结果联合组的反应率和中位生存期明显高于其他两组。结论多西他赛联合顺铂有较好疗效,单用顺铂不能延长患者的生存期。
出处 《中国误诊学杂志》 CAS 2011年第6期1317-1318,共2页 Chinese Journal of Misdiagnostics
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  • 1Spigel DR. Greco FA, Thompson DS, et al. Phase II study of cetuximab, docetaxel, and gemcitabine in patients with previously uutreated advanced non small-cell lung cancer[J]. Clin Lung Cancer,2010,11(3) :198- 203.
  • 2Jain AK. Hughes RS. Sandier AB, et al.A phase II study of concurrent chemoradiation with weekly docetaxel, carhopladn, and radiation therapy followed by consolidation chemotherapy with docetaxel and carboplatin for locally adwmced inoperable non small cell lung cencer (NSCLC)[J].J Thorac Oncol. 2009, 4 (6):722-727.
  • 3Schneider BJ, Kalemkerian GP. Kraul MJ,et al. Phase II study of celecoxib and docetaxel in non small cell lung cancer (NSOLC) patients with progression after platinum based therapy[J].J Thorac Oncol,2008,3(12):1154-1159.

同被引文献65

  • 1张剑,吴晴.恶性肿瘤时辰化疗的原理和研究进展[J].徐州医学院学报,2006,26(1):86-89. 被引量:9
  • 2李献文,金建华,王芳,陆文斌,顾小燕,张华,杨玉薇.多西紫杉醇周疗法加卡铂治疗晚期非小细胞肺癌的疗效[J].临床肺科杂志,2007,12(6):539-540. 被引量:7
  • 3徐叔云,魏伟主编.临床药理学[M].3版.北京:人民卫生出版社,2008:119.
  • 4李宗泰.临床药理学[M].北京:人民卫生出版社,1998.82~83.
  • 5Unant A,Pignon JP,Le Chevalier T.Adjuvant chemotherapy for non- small cell lungcancer:contribution of the International Adjuvant Lung Trial [J].Clin Cancer Res,2005,11(13):5017-5021.
  • 6Belani CP Eckardt J.Development of docetaxe] in advanced non- small cell lung cancer[J].Lung Cancer,2004,46(Suppl 2):S5-S11.
  • 7Belani CP,Fossella F.Elderly subgroup analysis of a randomized phase III study of doeetaxel plus platinum combfnations versus vfnorelbine plus cisplatin for first-line treatment of advanced non-small cell lung carcfnoma(TAX 326)[J]. Cancer, 2005,104(12): 2766-2774.
  • 8Kim D Y, Lee D H, Jang S J, et al.Phase I1 Study of S-1 Plus Either Irinotecan or Docetaxel for Non-small Cell Lung Cancer Patients Treated with More Than Three Lines of Treatment[J].Cancer Res Treat, 2011, 43(4): 212.
  • 9Chun S H, Lee J E, Park M H, et al.Gemcitabine Plus Platinum Combination Chemotherapy for Elderly Patients with Advanced Non-small Cell Lung Cancer: A Retrospective Analysis[J].Cancer Res Treat, 2011, 43(4): 217-218.
  • 10Szkorupa M, Klein J, Bohanes T, et al.Neoadjuvant chemotherapy and surgical treatment in advanced stages of non-small cell lung cancer[J]. RozhlChir, 2011, 90(8): 433-440.

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