卵巢浆液性和黏液性交界性肿瘤36例临床病理特点

Clinicopathological Characteristics of 36 Cases with Ovarian Mucinous/Serous Borderline Tumors

目的探讨卵巢浆液性和粘液性交界性肿瘤的临床病理特点。方法对钦州市第一人民医院收治的36例卵巢浆液性和粘液性交界肿瘤临床资料及病理特点进行回顾性分析。结果浆液性和黏液性交界性肿瘤缺乏特异的临床表现。Ⅰ期浆液性交界瘤17例（81%）,黏液性交界瘤12例（80%）。Ⅱ期浆液性交界瘤3例（14.3%）,黏液性交界瘤2例（13.3%）。Ⅲ期浆液性交界瘤1例（4.8%）,黏液性交界瘤1例（6.7%）。有4例浆液性交界瘤淋巴结受累。有3例浆液性交界瘤为非浸润性种植,1例浆液性交界瘤为浸润性种植,1例黏液性交界瘤为浸润性种植。治疗以手术为主。术后随访110年,有1例Ⅲ期黏液性交界瘤患者术后5年死亡,其余健在。结论卵巢浆液性交界瘤预后较好,肿瘤在卵巢表面生长常有腹膜种植。

Objective To explore the clinicopathological characteristics of ovarian mucinous/serous borderline tumors.Methods Retrospective study was undertaken to 36 cases of patients suffering ovarian mucinous/serous borderline tumors treated in our hospital.Results The ovarian mucinous/serous borderline tumors lacked for specific and differential clinical manifestation.At stage Ⅰ,borderline serous tumors occurred in 17 cases（81%）,and borderline mucinous tumors in 12 cases（80%）.At stage Ⅱ,borderline serous tumors occurred in 3 cases（14.3%）,and borderline mucinous tumors in 2 cases（13.30%）.At stage Ⅲ,borderline serous tumors occurred in 1 case（4.8%）,and borderline mucinous tumors in 1 case（6.70%）.4 patients with borderline serous tumors suffered from lymph node.Borderline serous tumors in 3 patients were non-invasive implantation;borderline serous tumors in 1 patient were invasive implantation;borderline mucinous tumors in 1 patient were invasive implantation.Treatment was chiefly based on surgery.In the follow-up of 1 to 10 years,1 case at Stage Ⅲ with borderline mucinous tumors died in 5 years after surgery,while other patients are still living.Conclusion Borderline ovarian serous tumors had better prognosis,tumors growing on ovarian surface usually had peritoneum implantation.