南方沿海地区念珠菌性阴道炎感染分析

Prevalence of Monilial Vaginitis in Coastal Areas of Southern China

目的探讨近两年南方高热高湿沿海地区念珠菌性阴道炎群体在不同季节、年龄、月经周期的发病情况以及治疗后稳定趋势状况。方法对妇科门诊就诊的8 099例阴道炎患者进行念珠菌检测,采用生理盐水涂片法和革兰染色及念珠菌培养。结果南方高热高湿沿海地区念珠菌性阴道炎发病率为24.694%(2000/8 099);育龄妇女患病率高于其他年龄段,差异有统计学意义(χ2=58.81,P<0.01);夏、秋比冬、春季节患病率高,差异有统计学意义(χ2=32.39,P<0.01);月经后1周患病率高于其它时期,差异有统计学意义(χ2=4.67,P<0.05);治疗后,阳性率随末次用药时间的延长而逐渐下降(趋势χ2=47.78,P<0.01)。结论南方高热高湿沿海地区念珠菌性阴道炎的感染率有所上升;与生育年龄呈正相关;夏、秋季节念珠菌性阴道炎的感染率高;月经后1周,念珠菌的阳性率最高,应重点预防。复查应选停药5 d后,因其结果趋于稳定。

Objective To discuss the prevalence of monilial vaginitis in different season,different age,different menstrual cycle and the tendency toward stabilization stable after the treatment in Southern coastal areas.Methods The methods of normal saline smear,Gram stain and cultivate were used to detecte the monilia from 8 099 gynecology outpatients with vaginitis.Results The morbility of monilial on Southern coastal areas is 24.694%（2 000/8 099）.The incidence of childbearing women were higher than other women（χ2=58.81,P〈0.01）.Detection rate of monilia in summer and autumn were higher than winter and spring with significant difference（χ2=32.39,P〈0.01）.Detection rate of Monilia in one week after menstruation（1 324 cases,29.69%） are higher than other period with significant difference（χ2=4.67,P〈0.05）.After treatment,the positive rate of monilia will gradually decreased with time extending（Cochran-Armitage test for trend χ2=47.78,P〈0.01）.Conclusion The incidence of monilial vaginitis has increased and has a positive correlation with the childbearing age;the infection rate of monilial vaginitis in Summer and Autumn were higher;The positive rate of Monilia in one week after menstruation were higher;the recheck should be performed in 5 days later of discontinue medication when the result tend stable.