摘要
目的观察妊娠期肝内胆汁瘀积症(ICP)对围生儿预后的影响及危害。方法:对186例住院分娩的妊娠期肝内胆汁瘀积症病例进行回顾性分析,并与正常孕妇对照研究。结果:妊娠期肝内胆汁瘀积症的早产率、产后出血量较正常孕妇组高(P<0.01),新生儿窒息率、围生儿死亡率、羊水污染率比正常孕妇组都高(P<0.05)。结论:妊娠期肝内胆汁瘀积症严重影响围生儿的预后,应早期诊断,积极治疗,严密监控以降低围生儿发病率及病死率。
Objective：To investigate the impact of intrahepatic cholestasis of pregnancy on perinatal prognosis of children. Methods： 186 cases with intrahepatic cholestasis of pregnancy in our hospital from 2008 to 2010 were retrospectively analyzed, normal pregnant were select for compara research. Results： Intrahepatic eholestasis of pregnancy can increase the incidence of preterm delivery,postpartum hemorrhage （ P 〈 0.01 ）, neonatal asphyxia, perinatal infant death rate and amniotic fluid pollution rate （ P 〈 0. 05）. Conclusion：Intrahepatie cholestasis of pregnancy seriously affect the prognosis of perinatal child and it should be early diagnosis, postive treatment and serious custodial care to reduce perinatal morbidity and mortality.
