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老年人冠状动脉介入术后造影剂对肾功能的影响 被引量:3

The Effection of Contrast Agent on Renal Function after Percutaneous Coronary Intervention in Elderly
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摘要 目的了解造影剂对老年人冠状动脉介入诊疗术后肾功能的影响。方法选择经皮冠状动脉介入治疗的老年患者40例,年龄(70.5±8.2)岁。全部选用低渗非离子造影剂,接受水化治疗(静脉水化)。测定造影前、造影后第1 d、第3 d、第7 d肾功能指标。结果尿α1微球蛋白术后第1 d、第3 d分别为(14.74±14.58)mg/L和(13.86±18.09)mg/L,与造影前(6.71±5.11)mg/L比较,显著升高(P<0.05),第7 d恢复到术前水平;血清尿素氮、肌酐、尿微量白蛋白、尿转铁蛋白、尿液IgG与术前比较,差异无统计学意义。按造影剂肾病诊断标准,仅1例诊断造影剂肾病(2.5%)。结论选用肾毒性小的造影剂、水化,能显著降低造影剂肾病的发生,即使出现肾功能损害,1周后可恢复正常。 Objective To understand the renal function influcence of contrast agent after coronary interventional therapy in elderly.Methods 40 elderly cases who were adopted percutaneous coronary intervention were studied.The mean age was 70.5±8.2 years.Low permeability and non-ionic contrast agent were selected to used.Hydration treatment were perfromed before treatment.Renal function was detected before angiography,1 d,3 d and 7 d post angiography.Results The urinary α1-microglobulin was(14.74±14.58)mg/L and 13.86±18.09 mg/L in 1 d and 3 d postoperative respectively,and there were significant Increased contrast with before angiography(6.71±5.11)mg/L(P0.05).However the level returned preoperative level in 7d after angiographt.blood urea nitrogen,creatinine,urinary albumin,urinary transferrin,IgG and preoperative urine were no significant difference contrast with before angiography.There only 1 case was diagnosed contrast nephropathy(2.5%) with diagnostic standards.Conclusion To choice contrast agent with less renal toxicity and hydration treatment can significantly reduce the incidence of contrast nephropathy,even if renal functional lession occured,renel function will recovered to normal after 1 week.
出处 《黑龙江医学》 2011年第3期189-190,共2页 Heilongjiang Medical Journal
关键词 冠状血管造影术 造影剂 肾功能衰竭 急性 危险因素 Coronary angiography Contrast agent Renal failure acute Risk factors.
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