青少年类风湿性关节炎患者下颌骨生长发育研究

Mandibular Development of Juvenile Rheumatoid Arthritis Patients

目的:从牙全景片上髁状突与下颌骨升支的比例变化分析青少年类风湿性关节炎对下颌骨生长发育的影响。方法:16例患有类风湿性关节炎的青少年女性患者,根据是否有可见的髁状突损伤分为研究组与对照组;选取3个生长发育阶段,生长高峰期前,生长高峰期,生长高峰期后,每个阶段相隔2年。研究组包括8名患儿患有类风湿性关节炎且伴有髁状突损伤,平均年龄在第一阶段10岁,在第二阶段12岁,在第3阶段14岁。另外8名患儿患有类风湿性关节炎,但是不伴有髁状突损伤为对照组,3个生长发育阶段年龄与研究组相同。拍牙全景片。在牙全景片上测量髁状突与下颌升支的比例。左右侧下颌升支分别测量,计算髁状突长度和下颌升支的高度。结果:髁状突比例在研究组和对照组明显的不同(P<0.01),研究组明显的低于对照组。研究组的变化从第一阶段到第三阶段是逐渐减少。结论:类风湿性关节炎伴有髁状突损伤的患者下颌升支发育明显的受限,且有随年龄增长加重的倾向。

Objective：The aim of this study was to investigate the effect of juvenile rheumatoid arthritis to the mandibular development from the ratio of condyle and ramus height on panoramic radiographs.Methods： 16 female juvenile rheumatoid arthritis female patients were selected and divided into study and control group according to the obvious condylar lesion.Three stages were followed,the peak of development and before and after the peak of development.The difference between every two stages was two years.The study group included 8 juvenile rheumatoid arthritis patients with condylar lesions and the control group included 8 juvenile rheumatoid arthritis patients without condylar lesions.The ratios of the condyle and ramus height was measured on panoramic radiographs.The results showed the ratio of condyle and ramus height was statistically significant different.It was lower in study group than in control group.Decrease was seen in study group from the first stage to the third stage.Conclusion： The mandibular development of juvenile rheumatoid arthritis patient with condylar lesion was significantly limited and increasing tendency was seen as the growing.