摘要
患者女,56岁。右口角斑块2年余。皮肤科情况:右口角见一2.2cm×1.4cm浸润性肤色斑块,中央偏淡红色,表面不平,边界清楚,与皮肤黏连,质硬。组织病理检查示:真皮中下部及皮下组织见多数基底样瘤细胞团块,瘤细胞形成巢状、条索状或蝌蚪样肿瘤团块,伴有大量管腔及囊腔样结构形成,部分腔内可见嗜酸性均一物质。间质明显增生,可见透明变性和黏液变性。未见角质囊肿及筛状结构形成。免疫组化染色示:肿瘤细胞上皮膜蛋白(EMA)和癌胚抗原(CEA)阳性,S100蛋白、角蛋白10(CK10)、角蛋白20(CK20)和GCDFP-15(gross cystic disease fluid protein-15)均阴性。诊断:汗管样小汗腺癌。本病临床罕见。治疗采用Mohs手术切除。
A 56-year-old woman presented with 2 years history of a 2.2cm×1.4cm skin-color firm plaque beside the right cheilion.The lesion was well-demarcated and fixed to the underlying tissue.The tumour consisted of atypical basaloid cells arranging in narrow cords and nests and partially forming ductular,adenoid and cystical structure in dermis and subcutaneous adipose tissue.Tadpole-like forms were observed.Squamous or follicular differentiation was not seen.Tumour cells showed positive reactivity to EMA and CEA but negative to S-100 protein,CK10,CK20 and GCDFP-15.Diagnosis：Syringoid eccrine carcinoma.This is an extremely uncommon case.The patient was treated with Mohs micrographic surgery.
出处
《中国皮肤性病学杂志》
CAS
北大核心
2011年第4期247-249,共3页
The Chinese Journal of Dermatovenereology
关键词
汗管样小汗腺癌
诊断
治疗
Syringoid eccrine carcinoma
Diagnosis
Therapy
