2,2-双(3-苯基-4-羟基苯基)丙烷的合成研究

Studies on synthesis of 2,2-bis(3-phenyl-4-hydroxyphenyl) propane

以邻苯基苯酚和丙酮为原料,盐酸为催化剂,巯基丙磺酸为助催化剂,通过缩合反应合成了2,2-双(3-苯基-4羟基苯基)丙烷(双OPP-A),研究了原料配比、催化剂用量、反应温度、反应时间等因素对反应的影响,通过实验确定了合成双OPP-A的最优条件为:n(邻苯基苯酚):n(丙酮):n(盐酸):n(巯基丙磺酸)=8:2:4:1,反应温度为60℃,反应时间24h,双OPP-A收率达到78.5%,经重结晶纯度达99.2%。产物通过红外光谱和核磁共振等进行了确证。

The 2,2-bis（3-phenyl-4-hydroxyphenyl） propane（bisOPP-A） was synthesized from o-phenylphenol and acetone by using hydrochloric acid as catalyst and 3-mercaptopropanesulfonic acid as catalytic promoter. The effect of molar ratio of starting materials,the reaction temperature and time on the reaction were studied. The optimum conditions for the synthesis of bisOPP-A are as follows：n（o-phenylphenol）：n（acetone）：n （hydrochloric acid）：n（3-mercaptopropanesulfonic acid） =8：2：4：1,reaction temperature is 60℃and reaction time is 24h,and the yield of bisOPP-A is 78.5%,the purity of the product after recrystaUization is 99.2%.The product was assigned by IR and ~1HNMR.