壮观霉素治疗猪支原体肺炎试验

Treatment Tests with SPECTINOMYCIN on Mycoplasmal Pneumonia of Swine

本试验用壮观霉素（速白治），通过控制试验和临床治疗试验对人工感染和自然感染猪支原体肺炎的病猪进行治疗试验。控制试验分三种不同剂量组，治疗１个疗程（５天）。１０毫克／千克体重的治愈率为７５％，治疗有效率为１００％。２０毫克／千克体重和３０毫克／千克体重的治愈率均为９１７％，治疗有效率为１００％。对照组（不治疗）自愈率为０，且病情均有加重。各组剖杀２头猪分离支原体，３个治疗组均为阴性，对照组均分离到支原体（２／２）。３个治疗组与对照组比较，平均增重差异极显著（Ｐ＜００１），但３个治疗组之间增重差异不显著。在四川省的四个规模化猪场对５２５头具有猪喘气病临床症状的猪用速白治，按１０毫克／千克体重治疗１～２个疗程后，用Ｘ线胸透随机抽查１５５头猪，治愈率达９２３％。

Using SPECTINOMYCIN(Vni Spect) to treat on the pigs which had been artificially infected or naturally effected with mycoplasmal pneumonia.The controlling test was divided into three agent groups,after one treatment cycle pperiod(5,days),the cure rate is:No.1 group(10mg per kg body weight)is 75%,No.2 group(20mg per kg body weight)is 91 7%,No.3 group (30mg per kg body weight)is 91 7%,too.The comparison group(no treatment)is O,and the disease became more serious.Selecting two pigs from every group to kill,the isolation result of pneumonia mycoplasma:Three treatment groups is negative(0/2),the comparison group is positive(2/2).The difference of average weight added between treatment groups and comparison group is obvious(P<0 01),but the difference among three treatment groups is not obvious. On four large scale pig farms in sichuan,Using vni spect(10mg per kg body weight)to treat on 525 pigs which had been infected with mycoplasmal pneumonia,after 5 to 10 days,the curl rate reached to 92 3%