环境水体中四溴双酚A的HPLC-MS/MS分析方法的建立与应用

Determination and application of TBBPA in water by high performance liquid chromatography-tandem mass spectrometry

四溴双酚A（tetrabromobisphenol A,TBBPA）是目前使用量最大的溴代阻燃剂。随着它的广泛应用,已经引起了大气、水体、沉积物和土壤等环境介质及相关生态系统的严重污染。建立了环境水体中TBBPA的高效液相色谱-串联质谱（HPLC-MS/MS）分析方法。该方法采用电喷雾电离（ESI）负离子模式进行扫描,定性离子对542.6/290.81,542.6/417.77,542.6/419.69,542.6/445.79,542.6/447.67,定量离子为542.6/447.67。方法检出限为1.2 ng/L,回收率为88.91%~95.98%。应用该方法对环渤海地区20个采样点的水样进行分析,均检测出TBBPA。结果表明,该方法适用于环境水体中TBBPA的检测。为我国环境水体中TBBPA的含量检测提供了方法和依据。

Tetrabromobisphenol A（TBBPA） is widely used throughtout the world as flame retardant.And it has caused extensive pollution of air,water,sediment,and soil,as well as their relevant ecosystems.A method for determination of TBBPA in the environment by high performance liquid chromatography—tandem mass spectrometry（HPLC-MS/MS） was developed.The spectral acquisition was done in the negative electron spray ionization utilizing multiple reaction monitoring of five parent-daughter ion pairs（m/z）： 542.6/290.81,542.6/447.67,542.6/419.69,542.6/445.79,542.6/447.67.The ion pair of 542.6/447.67 was used for quantitation.The detection limits was 1.2 ng/L and rcovery was 88.91%~95.98%.,TBBPA were detected in all the samples around Bo sea.The results showed that this method was applicable for monitoring TBBPA in environmental water.And this study provided a method for determination of TBBPA in environmental water.