摘要
目的探讨18F-FDG PET/CT双时相显像鉴别孤立性肺结节(SPN)良恶性的价值。方法对65例SPN病人分别在注药后1 h和2~3 h进行PET/CT双时相显像;对SPN的早期显像标准摄取值(SUV)、延迟显像SUV、滞留指数进行分析。结果经病理证实恶性36例、良性29例,其中良性结节包括炎性假瘤13例,结核球12例,硬化性血管瘤2例,肺腺瘤1例,隐球菌感染1例;恶性结节中包括10例磨玻璃结节。良性组、恶性组的早期显像SUV、延迟显像SUV、滞留指数差异均无统计学意义。结论 18F-FDG PET/CT双时相显像对SPN良恶性的鉴别诊断价值有限,尚需进一步研究。
Objective To assess the value of dual-phase 18F-FDG PET/CT in the differential diagnosis of a solitary pulmonary nodule. Methods Dual-phase 18F-FDG PET/CT study was conducted in 65 patients with imaging 1 and 2-3 hours after drug injection.The standard uptake value(SUV),delay imaging SUV,and retention index were analyzed. Results Of 65 nodules,36 were malignant,and 29 benign.Of the benign nodules,there were nflammatory pseudotumor(13 nodules),tuberculoma(12),sclerosing hemangioma(2),pulmonary adenoma(1),and infection of cryptococcus(1).Of malignant nodules,which included 10 ground-glass nodules.The differences of SUV,delay SUV and retention index were not statistically significant between benign group and malignant group. Conclusion The present study indicates the value of dual-phase 18F-FDG PET/CT is limited in differentiating malignant from benign solitary pulmonary modules.A further study of this topic is needed.
出处
《齐鲁医学杂志》
2011年第3期227-229,共3页
Medical Journal of Qilu
关键词
硬币病变
肺
诊断
鉴别
体层摄影术
发射型计算机
coin lesion
pulmonary
diagnosis
differential
tomography
emission-computed