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191株鲍曼不动杆菌的耐药性分析

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摘要 目的了解鲍曼不动杆菌的医院感染分布及耐药状况,为临床治疗提供依据。方法对本院2009年6月~2010年6月分离的191株鲍曼不动杆菌,采用标准纸片扩散法(K-B法)进行药物敏感性试验,并用WHONET 5.4软件进行统计分析。结果 191株鲍曼不动杆菌中,痰液分布率最高,占87.4%(167/191)。药敏结果显示,鲍曼不动杆菌对多黏菌素B最为敏感,敏感率为99.5%,其次是米诺环素和哌拉西林/他唑巴坦,分别为71.7%和56.0%;耐药率最高的抗生素是头孢曲松,为94.2%,对复方新诺明、哌拉西林、替卡西林/克拉维酸、美罗培南和亚胺培南的耐药率分别达到了74.3%、73.2%、72.8%、67.9%和66.0%。结论鲍曼不动杆菌是医院感染主要病原菌之一,并且对多种抗菌药物耐药,且多重耐药性明显。实验室应加强耐药性监测,以指导临床合理使用抗生素,提高疗效和减缓耐药株的产生。
出处 《海峡药学》 2011年第4期182-183,共2页 Strait Pharmaceutical Journal
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