青年人原发性肝癌24例诊疗分析

Analysis of diagnosis and treatment of young 24 cases with primary liver cancer

目的：探讨青年原发性肝癌（PLC）的临床诊疗特点。方法：选择PLC患者80例,随机分为青年肝癌组（年龄〈40岁）24例,非青年肝癌组（年龄≥40岁）56例,比较分析2组的临床症状、肝脏功能、病理类型、术后并发症发生率等。结果：青年组缺乏特异性临床表现的比例较非青年组高（P〈0.05~P〈0.01）,青年组胆管细胞癌比例较非青年组少（P〈0.05）。青年组肝脏功能较老年组好（P〈0.01）,术后并发症发生率较非青年组低（P〈0.05）。结论：青年人肝癌起病隐匿,早期诊断率低,手术耐受性高,治疗应尽量采用以根治性肝切除为主的综合治疗,术后并发症发生率低。

Objective：To investigate the clinical features and treatment of young patients with primary liver cancer（PLC）.Methods：A total of 80 cases of PLC were divided into 2 groups,young group（age40 years）,24 cases;non-young group（age≥40 years）,56 cases.The clinical symptoms,clinicopathologic features,clinical conditions of liver and the incidence of postoperative complications in the two groups were comparatively analyzed.Results：The cases in young group have less specific clinical manifestations than the cases in non-young group（P0.05-P0.01）;cholangiocarcinoma in the young group are less than that in non-young group（P0.05）,young group has a better liver fuction than that of non young group（P0.01）.Postoperative complications rate in young group is lower than in non-young group（P0.05）.Conclusions：Occult liver cancer onset,low early diagnosis and high operation tolerance occur in young PLC patients;surgery-predominant comprehensive therapy should be performed for young PLC patients to improve outcome.Low incidence of postoperative complications were also noted in young PLC patients.