感染后咳嗽80例诊治体会

Diagnosis of 80 Cases Cough after Infectious

目的:探讨联用顺尔宁(白三烯受体拮抗剂-孟鲁司特)与复方甲氧那明胶囊联合治疗感染后咳嗽的临床疗效。方法:80例在我院呼吸专科门诊诊为感染后咳嗽患者,随机分为治疗组与阳性对照组各40例,治疗组每天给予顺尔宁10mg口服;两组患者均给予口服复方甲氧那明胶囊或化痰等常规对症治疗,两组疗程均为14d。记录治疗前后的咳嗽症状积分的变化以及不良反应。结果:两组患者治疗14d后的咳嗽症状积分较治疗前的均有改善,而治疗组的咳嗽症状消失率较阳性对照组的更高(P<0.05)。结论:联用顺尔宁与复方甲氧那明胶囊治疗感染后咳嗽可明显提高疗效。

Objective： To investigate the effect of combination of singulair （ inhibitor of leukotriene receptor-montelukast） and methoxyphenamine compound on postinfectious cough. Method： 80 cases of outpatients with postinfectious cough were enrolled, and divided into treatment group and positive control group by randomization. Each group has 40 cases of outpatients. Both groups were administrated with methoxyphenamine compound or apophlegmatisant, while treatment group were extra-administrated with singulair 10 mg PO every day. Cough symptoms, as well as adverse effects, were evaluated and scored before and after treatment. Result： Both groups underwent improvement in cough symptoms after treatment. Treated group witnessed more potent efficacy in eliminating cough symptoms than positive control group （ P〈0.05 ）. Conclusion： Combination of singulair and methoxyphenamine compound has better effect than single use of methoxyphenamine compound on postinfectious cough.