心力衰竭心源性猝死的研究进展

Progress in the Study of Sudden Cardiac Death in Heart Failure

心源性猝死(SCD)是临床常见急重症,在心力衰竭患者中发病率较高。SCD发生由多种病因引起,其主要机制为心律失常。由于SCD病死率高,早期发现和预防在临床工作中显得尤为重要。近年来,关于SCD预警因素的研究越来越多,实验证明纽约心功能分级、左心室射血分数、心率变异性、T波交替及多种血清学指标均对SCD的预防具有指导意义,也进一步为SCD的治疗提供了客观依据。

Sudden cardiac death（SCD）is a kind of commonly-seen severe emergency in clinical work,and has a highter morbidity in patients with heart failure.There are various etiological factors of SCD,while its main pathogenesis is arrhythmia.Early detection and prevention is particularly important due to the high mortality.In recent years,there are more and more reseach of SCD predictors,such as NYHA heart functional class,left ventricular ejective fraction,heart rate variability,T wave alternans and multiple serum index.All the above can be used in guiding the prevention of SCD,and providing objective basis for the treatment of SCD.