3种治疗方案在2型糖尿病患者中的成本-效果分析

Analysis of cost-effectiveness of three different drugs in the treatment of type 2 diabetes mellitus

目的利用成本-效果分析方法,评价3种方案治疗2型糖尿病的药物经济学效果,为治疗2型糖尿病药物选择提供参考.方法 从采用二甲双胍缓释片、阿卡波糖胶囊和格列齐特缓释片治疗的2型糖尿病患者中各随机选取80例,分别为A组、B组和C组,比较其药物经济学效果和敏感性分析.结果 A组C/E 170.18,最小;C组⊿C/⊿E 6.87,小于其他两组.结论 从药物经济学的角度分析,二甲双胍缓释片治疗2型糖尿病方案最经济,但是格列齐特缓释片疗效最佳,在临床治疗中应根据具体情况合理选药.

Objective To explore the cost - effectiveness of three different drugs in the treatment of type 2 diabetes mellitus, to provide reference for choice drug. Methods From the patients using of metformin hydrochloride sustained release tablets, acarbose capsules,gliclazide sustained release tablets were randomly selected 80 eases, namely A group, B group and C group, compared the cost - effectiveness and sensitivity analysis. Results A group of patients with C/E was 170. 18, its value was minimal; C patients group of patients with △C/△E was 6. 87, smaller than the other two groups. Conclusion The metformin hydrochloride sustained release tablets in the treatment of type 2 diabetes mellitus is the most economical solution, but the effect of gliclazide sustained - release tablets is the best, choice of drug should be based on the different clinical conditions.