摘要迄今为止,全世界大约有3.5~4.0亿慢性乙型肝炎病毒（hepatitis B virus,HBV）感染者,血清学证据表明：约占全球人口总数1/3的人既往或正在感染HBV。每年有超过100万的患者死于HBV感染相关的肝衰竭、肝硬化和肝癌[1]。我国是HBV感染的主要流行区,现有慢性HBV携带者约1.2亿，’
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