噻虫嗪中间体3-甲基-4-硝基亚胺基四氢-1,3,5-噁二嗪的合成研究

Research on the Synthesis of 3-Methyl-4-nitroiminoperhydro-1,3,5-oxadiazine

对噻虫嗪中间体3-甲基-4-硝基亚胺基四氢-1,3,5-噁二嗪的合成进行研究。通过优化反应条件,使产品转化率达到90%以上,同时收率也能达到85%以上,高于以往的文献报道值。该方法操作简便,适用于工业化生产。

In this article,we make a detailed research on the synthesis of 3-methyl-4-nitroiminoperhydro-1,3,5-oxadiazine.By optimizing the conditions,a better way that can improve the conversion rate of 3-methyl-4-nitroiminoperhydro-1,3,5-oxadiazine has been found.The conversion rate is over 90%,and the yield is over 85%,both higher than any another literatures do.The route is easy to operate and applicable for manufacture.