2型糖尿病患者医院感染相关因素

Related factors for infections in patients with type 2 diabetes mellitus

目的研究2型糖尿病患者医院感染的相关因素,以制定相应对策,降低其感染率。方法选择2型糖尿病发生医院感染者48例(医院感染组)和同期住院未发生医院感染的2型糖尿病患者55例(对照组),比较2组患者入院时年龄、空腹血糖、糖化血红蛋白、住院时间、免疫水平、入院后侵袭性操作、抗菌药物及胰岛素泵使用情况。结果入院时医院感染组患者平均年龄(62.57±14.35)岁、空腹血糖(10.26±3.68)mmol/L、糖化血红蛋白(8.38±2.95)%、住院时间(21.38±10.77)d,均高于对照组[分别为(44.40±12.82)岁、(8.96±2.92)mmol/L、(6.73±2.57)%、(16.24±9.62)d],差异均有统计学意义(P<0.05);免疫性指标差异无统计学意义(P>0.05);医院感染组患者进行侵袭性操作率(16.67%)、使用抗菌药物种类≥2种比率(68.75%)均高于对照组(分别为3.64%、9.09%),对照组胰岛素泵使用率(67.27%)高于医院感染组(14.58%),差异均有统计学意义(P<0.05)。结论 2型糖尿病患者医院感染可受多种因素的影响,应加强监测,针对相关因素采取综合性措施,防止其医院感染的发生。

Objective To study the related factors and appropriate strategies for infections in patients with type 2 diabetes mellitus （DM）, so as to reduce nosocomial infection（NI） rate. Methods Forty-eight type 2 DM patients with NI （NI group）and 55 type 2 DM patients without NI （control group） during the same hospitalization period were selected , patients＇ age at admission , fasting blood sugar, glycohemoglobin, hospital stay, immunization level, invasive procedure , antimicrobial use , and continuous subcutaneous insulin infusion in two groups were compared. Results Patients＇ average age at admission （[62. 57± 14. 35] years old）, fasting blood sugar（j10. 26 ±3.68]mmol/L）, glycohemoglobin（[8. 38 ±2. 95]%）, and hospital stay（[21.38 ±10. 77]days） in NI group were higher than （[44. 40 ±12. 82] years old）, （[8. 96 ±2. 921 mmol/L）, （[6. 73 ±2. 57]%） , and （[16. 24 ±9. 62] days） respectively in control group,there was significant difference between two groups（all P〈0. 05） ;Immunization levels in two groups were not statistically significant（P〈0. 05） ; invasive procedure rate in NI group （16. 67%） and ≥2 typies of antimicrobial usage rate （68. 75%） in NI group were both higher than those （3. 64% ,9. 09%） of control group respectively, continuous subcutaneous insulin infusion rate in control group（67. 27%） was higher than that of NI group（14. 58%）, the difference was significant（P〈0. 05）. Conclusion Multiple factors can influence the occurrence of NI in type 2 DM patients, surveillance should be intensified , comprehensive strategies should be taken to prevent the occurrence of NI.