摘要
从四川省木里县采集的云南红豆杉 Ｔａｘｕｓ ｙｕｎｎａｎｅｎｓｉｓ的树皮中分得 ３个紫杉烷类似物，经解析其^（１）Ｈ，^（１３）ＣＮＭＲ、ＥＩＦＡＢ ＭＳ谱及ＤＥＰＴ实验证明此３个类似物为１－β－ｈｖｄｒｏｘｙ－ｂａｃｃａｔｉｎＩ（Ｉ）、 １０－ｄｅａｃｅｔｙｌｔａｘｏｌ（Ⅱ）、 ７， ９－ｄｉｄｅａｃｅｔｙｌｂａｃｃａｔｉｎ Ⅵ（ Ⅲ）。此 ３个化合物存在于红豆杉属的其它植物中，但首次从云南红豆杉中分出。
Three taxane diterpenoids were isolated from the bark of Taxus yunnanensis Cheng et L. K. Fu collected in Molin county, Sichuan Province. Their chemical structures were elucidated as 1-β- hydroxy baccatin I (I ); 10-deacetyltaxol(Ⅱ ) ; and 7,9-dideacetyl baccatin Ⅳ (Ⅲ) by ~1HNMR, ^(13)CNMR, EI and FABMS as well as DEPT spectrum. These compounds were isolated from T. yunnanensis Cheng et L. K. Fu for the first time even though they also existed in other species of Taxus L.
出处
《中草药》
CAS
CSCD
北大核心
1999年第7期484-487,共4页
Chinese Traditional and Herbal Drugs
基金
卫生部出国留学回国人员基金
关键词
云南红豆杉
紫杉烷类似物
抗肿瘤活性
红豆杉
Taxus yunnanensis Cheng et L. K. Fu l-β-hydroxy baccatin
10-deacetyltaxol
7, 9-dideacetyl baccatin Ⅳ
