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高半胱氨酸对血管内皮细胞功能影响的实验研究进展 被引量:4

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摘要 高半胱氨酸(Hcy)是体内甲硫氨酸代谢的中间产物。先天性或获得性Hcy代谢异常导致的Hcy增高已成为动静脉血栓形成的一个独立危险因素。本文主要就Hcy对血管内皮细胞存活力、物理屏障、舒张功能、抗凝、纤溶等功能的影响进行综述,并对Hcy影响血管内皮细胞功能的机制作一介绍。
出处 《国外医学(输血及血液学分册)》 1999年第3期148-151,共4页 Foreign Medical Sciences(Section of Blood Transfusion and Heanatology)
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  • 1Suresh C Tyagi,Lane M Smiley,Vibhas S Mujumdar. Reduction-oxidation (Redox) and vascular tissue level of homocyst(e)ine in human coronary atherosclerotic lesions and role in extracellular matrix remodeling and vascular tone[J] 1998,Molecular and Cellular Biochemistry(1-2):107~116

同被引文献47

  • 1中华神经科学会 中华神经外科学会.各类脑血管病诊断要点[J].中华神经科杂志,1996,6:379-379.
  • 2Boushey CJ,Beresford SA,Omenn GS,et al.A quantitativeassessment of plasma homocysteine as a risk factor for vasculardisease:probable benefits of increasing folic acid intakes[J].JAMA,1995,274:1049-1057.
  • 3Romerio SC,LinderL,Nyfeler J,et a.l Acute hyperho-mocysteinemia decreasesNO bioavailability in healthy a-dults[J].Atherosclerosis,2004;176:337-344.
  • 4Boushey CJ,Beresford SAA,Omenn GS,et al.A quantitative assessment of plasma homocysteine as a risk for vascular disease[J].JAMA,1995,274:1049-1057.
  • 5Morita H,Taguchi J,Kurihara H,et al.Genetic polymorphism of 5,10-methylenetetrahydrofolate reductase(MTHFR)as a risk factor for coronary atrery disease[J].Circulation,1997,95:2032-2036.
  • 6Brattstrom L.Common mutation in the methylenetetrahydrofolate reductase gene offers no support for mild hyperhomocysteinemia being a causal risk factor for cardiovascular disease[J].Circulation,1997,96:3805-3806.
  • 7Harpel PC,Chang VT,Borth W.Homocystenine and othersulfhydryl compounds enhance the binding of lipoproteina tofibrin:a potential biochemical link between thrombosis,atherogenesis and sulthydryl compound metabolism[J].ProcNatl Acad Sci USA,1992,89:10193-10197.
  • 8Welch GN,Loscalzo J,Homocysteine and arteriosclerosis.N Engl Jmed,1998;338∶1042-1050.
  • 9StangerO,FowlerB,HerrmannW.Folate therapy and in-stentrestenosis[J].NEngl JMed,2004,351:1259-1260.
  • 10Arnesen E,Refsum H,Bonaa KH,et al.Serum totalhomocysteine and coronary heart disease[J].Int JEpidimiol,1995,24:704.

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