不同病因患者脾切除前后血液流变学指标的变化

The Hemorheological Changes Before and After Splenectomy in Different Diseases

对９０例不同疾病（外伤性脾破裂３０例、肝硬变脾亢３０例、特发性血小板减少性紫癜３０例）脾切除前后血液流变学指标的变化进行了比较，发现术前肝硬变脾亢和特发性血小板减少性紫癜患者全血粘度和血小板聚集功能明显低于对照组（Ｐ＜０．０５～０．０１），提示多种因素可导致和加重术前出血症状。术后近期３组脾切除患者和对照组患者血液流变学指标均有升高，是术后高凝期，应予重视。术后远期３组脾切除患者全血粘度仍为高值，血小板聚集功能增强，但导致的原因并不相同。对增高明显者，为防止脾切除后血栓和栓塞形成，应采取针对性的预防和治疗措施。

Comparatively examined the hemorheological changes in 90 patients with different diseases (A.traumatic spleen rupture 30,B.hypersplenism 30,C.idiopathic thrombocytopenic purpura 30) before and after splenectomy.It was found that the blood viscosity and platelet adhesion in group B and C were lower than that in the control group befroe splenectomy (P<0.050.01)WTBZ,suggesting many factors may cause and aggravate bleeding in these two groups before operation.Shortly after operation,the indications,of hemorheology in the three splenectomized groups and control group increased.Much attention should be paied to these indications because this was the stage of high coagulation.In the long period after splenectomy,the blood viscosity and platelet adhesion in the three splenectomized groups remained in high level,but the leading causes were various.To prevent thrombosis and embolism after splenectomy,direct measures of prevention and treatment should be taken for patients with high level of indications.