卡文辅助直肠癌患者术后恢复的临床效果研究

The clinical effect on the Impact of Kabiven assisting rectal cancer patients of postoperative recovery

目的探讨静脉高营养支持辅助直肠癌患者术后恢复的临床效果。方法对华西医院结直肠外科专业治疗组2009年1月～2009年12月期间诊断为直肠癌的患者根据术后是否输入卡文分组进行研究,比较两者之间的临床疗效。结果术后1周,治疗组白细胞计数、中性粒细胞百分率、淋巴细胞百分率和单核细胞百分率均高于对照组(P<0.05);但血清清蛋白水平两组之间差无统计学意义(P>0.05)。治疗组在术后首次排便和经口进食时间上早于对照组(P<0.05),但术后排气时间和下床活动时间上两者差异无统计学意义(P>0.05)。在术后并发症发生率上,两者差异无统计学意义(P>0.05)。结论直肠癌术后患者采用卡文进行肠外高营养能够在一定程度上促进患者术后恢复,且具有一定的安全性。

Objective To evaluate the impact of Kabiven used in parenteral nutrition（PN）on clinical effect in postoperative period of rectal cancer.Methods Diagnosed rectal cancer patients of Department of Anal—Colorectal Surgery of West China Hospital between Jan.2009 to Dec.2009 were assigned into two groups depending on whether Kabiven was used in their treatment.Clinical effect was evaluated by comparison of there two groups.Results All the white blood cell count,percentage of granulocyte,percentage of lymphocyte and percentage of peripheral blood monocytes of experiment group is lower than that of control group and is of statistical significance（P0.05）whereas the difference of plasma albumin between the two group has no statistical significance.The postoperative time of oral intake in experiment group is earlier than in control group（P0.05）.Difference of the postoperative time of passing gas,time of ambulation and the percentage of post-operative complication is of no statistical significance.Conclusion Kabiven used in parenteral nutrition（PN） in postoperative period of rectal cancer may facilitate the recovery and this usage is of certain safety.