黄石市2008-2010年上半年手足口病流行病学分析

Epidemiological analysis of hand-food-mouth disease in Huangshi City(2008-2010.6.30)

目的分析黄石市2008-2010年上半年手足口病发病情况,探讨流行规律,为制定手足口病防控策略提供科学依据。方法采用描述性流行病学方法,对黄石市手足口病疫情报告资料进行统计分析。结果 2008-2010年上半年黄石市共发生手足口病4 666例,死亡2例,发病率有明显上升趋势。全年均有病例报告,但有明显的季节性发病高峰,主要集中在第15～30周;发病年龄主要集中于5岁以下年龄组,占总发病数的96.25%,发病率男性高于女性;发病职业以散居儿童、幼托儿童为主,分别占总发病数的70.04%和25.68%;病原监测结果提示由EV71、COXA16和其他肠道病毒混合感染,2010年主要由EV71引起,占送检样本的37.50%。结论手足口病发病具有明显的季节性和年龄、性别、职业差异,应注重重点人群监管,加强疫情监测,减少发病和死亡。

Objective To analyze the epidemiological characteristics of hand-foot-mouth disease（HFMD） in Huangshi city from 2008 to the first half of 2010,so as to provide scientific evidence for the effective prevention and control of HFMD.Methods Descriptive epidemiological analysis was conducted for the data obtained from HFMD epidemic in Huangshi city.Results 4666 cases of HFMD were reported in Huangshi city from 2008 to the first half of 2010,including 2 deaths.The incidence of HFMD increased significantly.HFMD case was reported through out the year with clear seasonal peak.Most cases occurred during the period of 15 to 30 weeks,children under 5 years old accounted for 90.44% of the total reported cases.There was significant statistical difference with other age groups（χ2=50826.34,P0.01）;The incidence of male was higher than female and was of statistical significance（χ2=576.52,P0.01）.High incidence was also found in the scattered children and Kindergarten＇s children,accounted for 70.04% and 25.68% respectively.The result of pathogen monitoring suggested that HFMD was co-infected with enterovirus71（EV71）,coxsacjievirus16（COXA16） and other entero-viruses in Huangshi city.HFMD was mainly caused by EV71 in 2010,accounting for 37.50%. Conclusions There was significant seasonal,age,gender and occupational difference in the incidence of HFMD,therefore,focus should be put on the key population and epidemic surveillance should be strengthened,so as to reduce morbidity and mortality.