摘要
[方法]1-(4-氯苯基)-3-吡唑醇是一种重要农药中间体,以对氯苯肼为原料经环合、氧化,合成1-(4-氯苯基)-3-吡唑醇。[结果]在优化的反应条件下,1-(4-氯苯基)-3-吡唑醇的反应总收率为72.5%(以对氯苯肼计),含量为99.2%,其结构经红外和氢谱核磁分析确证。[结论]该工艺具有反应条件温和、产品收率高等优点,适合工业化生产。
[Methods]As an important intermediate of pesticides,1-（4-chlorophenyl）pyrazolidin-3-one could besynthesized by the cyclization and oxidation from the raw material 4-chlorophenylhydrazine.[Results]Under the optimalcondition,the total yield was 72.5%based on 4-chlorophenylhydrazine and the purity was 99.2%.The structure of theresulting product was confirmed by IR and1H NMR.[Conclusions]The process exhibited mild reaction conditions andhigh yield,and is suitable for industrial production.
出处
《农药》
CAS
北大核心
2011年第5期327-328,349,共3页
Agrochemicals
基金
国家自然科学基金(20702051)
浙江省教育厅科研计划项目(Y200907685)
浙江省化学工程与新材料研究生教育创新示范基地(2009)
