宫颈锥切术对阴道镜检查的病理分级及其临床应用的再评价

Revaluation of cervical conization to pathological grading and clinical application of vagina bronchoscopy

目的比较宫颈上皮内瘤变(cervical intraepithelial neoplasia,CIN)阴道镜宫颈活检结果与宫颈锥切术后病检结果的差异,并评价宫颈多点活检在CIN诊断中的准确性和宫颈锥切术的诊治价值。方法 102例阴道镜活检诊断为CIN的患者行宫颈锥切术,对比手术前后的病理结果。结果设同一病理级别相符,81例(79.4%)宫颈锥切术与术前阴道镜活检病理结果符合;21例结果不符合,其中术后结果较严重者13例,较轻者8例。结论阴道镜下活检是诊断CIN的一种简单而有效的方法,宫颈锥切术可以弥补阴道镜下活检的缺陷,并且有治疗作用。

Aim To investigate the differences of pathological results between multiple sites biopsy and knife cervical conization,and to evaluate the accurancy of cervix biopsy,and the diagnostic and therapeutic value of cervical conization for the patients with cervical intraepithelial neoplasia（CIN）.Methods 102 patients who were diagnosed CIN with pathologic histology of vaginoscope were operated on conization of cervix,and the pathologic results before and after the operation were compared.Results On the premise that the coordinate pathological levels were the same,81 cases（79.4%）were accordant with cervix biopsy results after conization,while 21 cases were not.Among the 21 cases,13 patients＇diagnostic results after conization were more serious than that of biopsy,and 8 patients were milder.Conclusion Pathologic histology with vaginoscope is a simple and effective method for diagnosing CIN.Conization of cervix can remedy the defect of the pathologic histology with vaginoscope and shows a therapeutical effect.