糖尿病患者瞬态诱发耳声发射对侧抑制现象的临床研究

Contralateral suppressions of transient evoked otoacoustic emissions in diabetes mellitus patients

目的:研究听力正常的糖尿病患者瞬态诱发耳声发射(TEOAE)对侧抑制现象。方法:分别对30例听力正常的糖尿病患者(糖尿病组)及30例健康对照者(对照组)行纯音听阈、声导抗、TEOAE检测,并通过在其对侧耳中加入60 dB SPL的宽带噪声后TEOAE对侧抑制效应测试以评估其传出神经功能。结果:糖尿病组受试者的纯音听阈及TEOAE的幅值稍低于对照组,但两者间差异无统计学意义;其TEOAE的对侧抑制效应低于对照组,其中在2000 Hz及4000 Hz处差异有统计学意义(P<0.05)。结论:糖尿病患者在其外周听力尚处于正常状态时,其听觉传出神经的功能即已发生了改变。

Objective：To investigate the contralateral suppressions of transient evoked otoacoustic emissions（TEOAE） in diabetes mellitus patients with normal hearing.Method：The pure tone audiometry,acoustic immittance and TEOAE tests were performed in 30 diabetes mellitus patients with normal hearing and 30 healthy controls.The efferent system functions were evaluated by contralateral suppression of TEOAE.Result：There were no significant differences of pure tone thresholds and amplitudes of TEOAE between the two groups.The contralateral suppressions of TEOAE in diabetes mellitus patients were significantly lower than that in controls（P0.05 at 2 000 and 4 000 Hz respectively）.Conclusion： The nerve functions of central nerve system can be damaged in diabetes mellitus patients with normal hearing.