摘要
目的:探讨大剂量谷维素联合β-受体阻滞剂治疗心血管神经症的疗效。方法:对在本院就诊的74例心血管神经症的患者进行不同治疗方法的分组对照研究。观察组给予大剂量谷维素联合β-受体阻滞剂治疗;对照组常规治疗,2周后对患者进行随访,调查疗效。结果:观察组和对照组各周HAMD评分、HAMA与心血管神经症评分较治疗前均有显著下降。治疗各周后两组HAMD评分与HAMA差异有统计学意义(t1=2.343,2.252;t2=2.317,2.306;t4=2.298,2.318;t6=2.250,2.431),P<0.05。观察组在治疗后第1、2、4、6周的减分率分别为53.63%、66.44%、79.58%和83.74%。而对照组治疗1、2、4周后减分率无明显变化,两组差异有统计学意义(χ2>3.834)。结论:大剂量谷维素联合β-受体阻滞剂治疗心血管神经症疗效确切,值得临床推广应用。
Objective： To evaluate high-dose oryzanol combined with β-blockers treatment of cardiovascular neurosis patients.Methods： 74 patients with cardiovascular neurosis in our hospital treated with different methods,observation group treated with high dose oryzanol combined β-blockers,control group with conventional treatment,patients were followed up after two weeks.Results： The observation group and control group weekly HAMD score,HAMA scores and cardiovascular neurosis than before treatment were significantly lower.Two weeks after the treatment of the HAMD score and HAMA were significantly different,（t1=2.343,2.252;t2=2.317,2.306;t4=2.298,2.318;t6=2.250,2.431,P0.05）.The observation group 1,2,4,6 weeks after treatment,reduction rate was 53.63%,66.44%,79.58% and 83.74%.The control group 1,2,4 weeks after treatment no significant changes in reduction rate,the difference of two groups were significantly（χ23.834）.Conclusion： High-dose oryzanol combined β-blockers treatment of cardiovascular neurosis is effective,and it is worthy of clinical application.
出处
《中国当代医药》
2011年第12期42-43,共2页
China Modern Medicine
