噻托溴铵治疗稳定期慢性阻塞性肺疾病临床研究

目的研究噻托溴铵治疗稳定期慢性阻塞性肺疾病(COPD)临床疗效。方法将70例门诊患者随机分为研究组和对照组,每组各35例,对照组给予吸氧、吸入沙美特罗/氟替卡松(舒利迭)等治疗,研究组在对照组基础上吸入塞托溴铵,疗程3个月。对临床资料和治疗过程进行回顾性分析。结果研究组呼吸困难改善30例,有效率85.71%,对照组呼吸困难改善22例,有效率62.86%,两组对比差异有统计学意义(P<0.05)。同时,观察治疗前后两组患者肺功能改善情况,两组对比差异有统计学意义(P<0.05)。结论在内科治疗基础上,吸入塞托溴铵可以明显改善稳定期COPD患者的呼吸困难症状及肺功能。

Objective To studay the clinical effect of Tiotropium in the treatment of Lung function of Chronic Obstructive Pulmonary Disease COPD in Stationary Phase.Methods 70 COPD in Stationary Phase patients were randomly divided into treatment gyoup 30 cases and the control group 30 cases.The control group was given oxygen,Salmeterol Xinafoate And Fluticasone Propionate Powder For Inhalation Seretide,et cetera.The treatment gyoup was given Tiotropium on basis over 3 months.Then the clinical data and the treatment course were retrospectively analyzed.Results In the treatment gyoup 30 cases were effective in ameliorate dyspnea,the total effective was 85.71%.In the control group,22 cases were effective in ameliorate dyspnea the total effective was 62.86%.There were significant differences between the effect rate of two groups （P0.05）.At the same time ,Lung function of the treatment group was excellence.There were significant differences between the effect rate of two groups（P0.05）.Conclusion The tiotropium has the effection in the treatment of dyspnea and Lung function of COPD in Stationary Phase.