参松养心胶囊治疗室性早搏的效果

Effect of shensongyangxin capsule on ventricular premature beat

目的:观察参松养心胶囊不同治疗方法对室性早搏治疗的疗效。方法:98例室性早搏的入选病例均使用参松养心胶囊并美托洛尔联合治疗,治疗一周后,随机均分为两组:一组持续使用参松养心胶囊联合美托洛尔治疗3个月(持续治疗组),另一组使用参松养心胶囊联合美托洛尔治疗1个月后停用参松养心胶囊1周,再继续原方案治疗(间断治疗组),观察两组室性早搏发作的情况。结果:治疗1月时,两组效果无显著差异(P>0.05),停用参松养心胶囊1周内,间断治疗组早搏发生率(65.1%,28/43)明显高于持续治疗组(2.4%,1/41)(x2=36.47,P<0.05),两组在3个月后抗心律失常作用方面没有显著差别(P>0.05)。结论:参松养心胶囊在治疗室性早搏过程中,需要持续给药,如果短期中断治疗可出现病情反弹,再加用参松养心胶囊治疗仍然有效,对长期室性早搏的控制无显著影响。

Objective： To investigate the therapeutic effects of different therapeutic methods with shensongyangxin capsule on ventricular premature beat（VPB）.Methods： A total of 98 VPB patients were given shensongyangxin capsule and metoprolol treatment.After one week,the patients were randomly averagely divided into two groups： one group continued using shensongyangxin capsule and metoprolol treatment for three months（continuing treatment group）,the other group received shensongyangxin capsule and metoprolol treatment for one month,but no received shensongyangxin capsule for one week,then continued the original program of treatment（interruption treatment group）.Attacks of VPB were observed in the two groups.Results： One month after treatment,there was no significant difference between the two groups in therapeutic effects（P0.05）.During no received shensongyangxin capsule in one week,VPB incidence in interruption treatment group（65.1%,28/43） was significantly higher than that of continuing treatment group（2.4%,1/41）,x2=36.47,P0.05.Three months after treatment,there was no significant difference between the two groups in effects of anti-VPB（P0.05）.Conclusion： During treatment of ventricular premature beat by shensongyangxin capsule needs sustained drug delivery,short-term interruption of treatment can lead to disease bounce,but shensongyangxin capsule treatment continues again still has effect,it has no significant difference for effect on long-term control of ventricular premature beat.