凉血化瘀法和补肾法对肾小球肾炎大鼠血液流变学的影响

Effect of TCM Method Cooling the Blood and Dissipating Blood Stasis and Kidney Tonifying on Hemorrheology of the Rat with Experimental Glomerulonephritis

采用大鼠肾毒血清性实验模型，分为凉血化瘀治疗组、补肾治疗组和空白对照组，各灌服８周后杀检，测定各组血液流变学指标并进行组间比较。结果表明：凉血化瘀治疗组各项血液流变学指标（全血粘度、血浆比粘度、红细胞压积、纤维蛋白原含量）均明显优于病理组，组间比较具有显著性差异；补肾组和病理组之间相比无显著性差异。说明凉血化瘀法对于实验性肾小球肾炎大鼠血液流变学指标的改善作用强于补肾法。

Dividing the experimental nephrolytic serum rat models into 3 groups: treatment group with cooling the blood and dissipating blood stasis method, group with kidney tonifying method and the blank control group, after filling for 8 weeks put them to death and then assay the hemorrheology indices of each group. The results show the hemorrheology indices of treatment group with cooling the blood and dissipating blood stasis method, which include whole blood viscosity, plasma comparing viscosity, hematocrit and fibrinogen content, are all markedly better than pathological group. The inter group comparison also differs greatly. But there is no obvious difference between the group with kidney tonifying method and the blank control group. It indicates that the TCM method of cooling the blood and dissipating blood stasis is more effective than the kidney tonifying method on improving the rat hemorrheology indices with experimental glomerulonephritis.