齿龈内阿米巴感染与口腔疾病关系的调查

Investigation on the Relationship between Entamoeba Gingivalis Infection and Oral Diseases

目的:探讨齿龈内阿米巴感染与口腔疾病的关系,为有效治疗口腔疾病提供依据.方法:消毒棉签涂取受检者口腔病变处,生理盐水涂片后铁苏木素染色进行显微镜检查.结果:牙周炎与冠周炎、龈缘炎之间的感染率差异无显著性(P>0.05);牙周炎与龋齿、口腔溃疡、牙髓炎、对照组之间的感染率差异有显著性(P<0.01);齿龈内阿米巴滋养体吞噬白细胞的平均数,牙周炎为4.2,龋齿为1.3,口腔溃疡为0.7,对照组为0.3牙周炎是龋齿的3.23倍(P<0.01),口腔溃疡的6.00倍(P<0.01),对照组的14倍(P<0.01);龋齿是口腔溃疡的1.86倍(P>0.05),对照组的4.33倍(P<0.01).结论:齿龈内阿米巴感染与口腔疾病有关.齿龈内阿米巴吞噬大量白细胞,降低了口腔免疫力,有利于致病菌的生长繁殖,促进炎症的发生.

Objective：To investigate the relationship between Entamoeba gingivalis infection and oral diseases,and to provide a basis for effective treatment of oral disease.Methods：Using sterile cotton swab to swab the oral lesion of patients,smeard it with physiological saline,the smear was stained with hematoxylin iron and was observed under microscopy.Results：There were no significant differences among the infection rate of paradentitis,pericoronitis and marginal gingivitis（P0.05）,but there were significant differences among the infection rate of paradentitis,dental caries,canker sore,pulpitis and control group respectively（P0.01）.Average number of leukocyte which capturing amoeba trophozoite were：paradentitis 4.2,dental caries 1.3,canker sore 0.7,control group 0.3.The averages number of periodontitis was 3.23, 6.00,14 times higher than that of dental caries（P0.01）,oral ulcer（P0.01）,control group（P0.01） correspondingly;the average number of dental caries was 1.86,4.33 times higher than that of oral ulcer （P0.05）,control group（P0.01）.Conclusion：There is positive relationship between oral diseases and Entamoeba gingivalis infection in human gingival.