丙泊酚复合芬太尼用于无痛胃镜的临床观察

The Clinical Observation of Propofol Combined with Fentanyl Used in Analgesia Gastroscopic Examination

目的观察异丙酚复合芬太尼静脉麻醉用于胃镜检查的效应。方法 180胃镜检查患者,随机分为三组。A组为对照组,在局部麻醉下完成胃镜检查;B组为丙泊酚组,静脉注入丙泊酚2 mg/kg;C组为丙泊酚芬太尼组,先静脉注射芬太尼0.05 mg,再静脉注入丙泊酚2 mg/kg。观察3组麻醉效果、丙泊酚总用量及麻醉清醒时间。结果 B、C两组麻醉优良率显著高于A组。C组丙泊酚平均用量少于B组(P<0.05),两组清醒时间无显著性差异。结论异丙酚复合芬太尼静脉麻醉用于胃镜检查安全有效,操作方便,应大力推广。

Objective To observe the anesthetic effect of propofol combined with fentanyl in gastroscopic examination.Methods 180 patients were randomly divided into three groups.Group A was the contrast group which was under local anesthesia in gastroscopic examination.Group B was the propofol group with 2 mg/kg propofol injection.Group C was the propofol and fentanyl group with firstly 0.05 mg fentanyl injection and then 2 mg/kg propofol injection.The Anaesthetic effect,total dose of propofol and consciousness recovery time were recorded.Results The effects of anesthesia were better in group B and C than in group A.In group C,the total dose of propofol was less than that in group B（P0.05） and the consciousness recovery time showed no difference between the two groups.Conclusion Propofol combined with fentanyl is a safe and tolerant anesthetic method for gastroscopic examination,which should be promoted vigorously.