2-氨基-N-甲基-N-环己基苯磺酰胺的合成研究

Study of the Synthesis of 2-Amino-N-methyl-N-cyclohexyl benzene sulfonylamide.

以邻硝基氯苯和环己酮为原料，经氯磺酰化、氨烷基化，再缩合、还原合成了酸性染料中间体２ － 氨基－ Ｎ－ 甲基－ Ｎ－ 环己基苯磺酰胺，讨论和比较了各种合成方法，确定了较佳的工艺条件，试生产总收率达７０ ％ 。

The acid dye intermediate,2-amino-N-methyl-N-cyclohexyl benzene sulfonylamide was synthesized by chlorosulfonylation,aminoalkylation,condensation and reduction from nitrochlorobenzene and cyclohexanone with a total yield 70%.Each of synthetic methods was discussed and compared,and the optimum conditions were selected.