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小剂量阿糖胞苷姑息治疗65岁以上老年人急性髓系白血病32例 被引量:2

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摘要 目的分析小剂量阿糖胞苷(Ara-C)治疗65岁以上老年人急性髓系白血病(AML)的临床疗效。方法回顾性分析32例65岁以上老年AML患者的临床资料,包括基础疾病、主要症状、临床特征、骨髓象、外周血、染色体、免疫分型、应用小剂量Ara-C化疗效果等。Ara-C15mg/m^2,皮下注射,2次/d。结果32例老年患者中,完全缓解(CR)3例(9.3%),部分缓解(PR)19例(58.3%),总有效率68.6%;FLT3-ITD阳性的患者疗效差,有染色体复杂异位的患者疗效差。结论小剂量Ara-C姑息性治疗65岁以上AML患者有一定疗效,在一定程度上可以提高患者的生活质量,延长生存期。
出处 《白血病.淋巴瘤》 CAS 2011年第4期243-244,共2页 Journal of Leukemia & Lymphoma
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参考文献8

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二级参考文献32

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