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透明质酸在恶性血液病中作用的研究进展 被引量：1

Advance of hyaluronon in malignant hematological diseases
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摘要 透明质酸（HA）是一种在体内广泛存在的非硫酸化糖胺聚糖。HA的异常表达与恶性血液病的进展密切相关，HA与其受体CD44、RHAMM等的相互作用参与血液系统恶性肿瘤的增殖、运动、迁移、侵袭以及多药耐药等过程。根据近年来有关的最新文献报道，对HA在肿瘤中的研究以及在恶性血液病进展中的作用进行综述。 The hyaluronon （HA） is an extensive existing non-sultmucus glycosaminoglycan, l＇he abnormal expression of HA is closely related to the development of malignant hematological diseases. The interation between HA and its receptors, such as CD44, RHAMM, participate in the process of the proliferation, movement, migration, invasiveness and multi-drug resistence in tumors. According to the latest published literatures in recent years, the the studies of HA in tumors, and the functions of HA in the development of malignant hematological diseases are reviewed in this article.
作者 蔡淑贤(综述) 林艳娟(审校)
机构地区 福建医科大学附属协和医院血液科福建省血液病研究所
出处 《白血病．淋巴瘤》 CAS 2011年第4期251-253,共3页 Journal of Leukemia & Lymphoma
基金 福建省自然科学基金（2007J0084）
关键词 透明质酸 血液肿瘤 Hyaluronic acid Hematologic neoplasms
分类号 R733 [医药卫生—肿瘤]
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参考文献20

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二级参考文献1

共引文献3

同被引文献24

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白血病．淋巴瘤
2011年 第4期

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