360例外科围术期预防性应用抗菌药物调查分析

Perioperative Use of Prophylactic Antibiotics in Surgical Patients:Review of 360 Cases

目的:了解外科围术期预防性应用抗菌药物现状及合理性。方法:采用回顾性调查方法,根据抗菌药物应用合理性判断标准进行判断。结果:360例手术病历抗菌药物预防性使用率100.00%。其中,Ⅰ类切口手术204例,合理的有2例(0.98%);Ⅱ类切口手术146例,合理9例(6.16%);Ⅲ类切口手术10例,合理1例(10.00%),总合格率为3.61%。用药时间正确16例(4.44%);选用的药物超标准的320例(88.89%),术后用药时间正确的13例(3.61%)及联合用药不合理(包括无指征)的191例(53.06%)。结论:围术期预防性应用抗菌药物的合理性不容乐观。

OBJECTIVE： To investigate the status quo and rationality of the perioperative use of prophylactic antibiotics in surgical patients.METHODS： By a retrospective study,the rationality of perioperative use of prophylactic antibiotics was evaluated in accordance with the criteria for the rational use of antibiotics.RESULTS： Of the 360 cases,the rate of antibiotic use was 100.00%.The rational use of antibiotics was noted in only 2 cases（0.98%） of the total 204 type Ⅰ incision patients,9 cases（6.16%） of the total 146 type Ⅱ incision cases and 1（10.00%） of the total 10 type Ⅲ incision cases,with a total rational drug use rate of 3.61%.16 cases（4.44%） were rational in medication time;Off-standard use was noted in 320 cases（88.89%）;13 cases（3.61%） were rational in postoperative administration time;191 cases（53.06%） were irrational in drug combination（including off-indication use）.CONCLUSION： The perioperative use of prophylactic antibiotics in surgical patients is far from optimistic.